Fabrication of carboxymethylcellulose hydrogel containing β-cyclodextrin-eugenol inclusion complexes for promoting diabetic wound healing

J Biomater Appl. 2020 Jan;34(6):851-863. doi: 10.1177/0885328219873254. Epub 2019 Sep 2.
No abstract available

Keywords: Inflammation; angiogenesis; eugenol; hydrogel; nuclear factor kappa-B.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Animals
  • Antioxidants / chemistry*
  • Antioxidants / pharmacology
  • Carboxymethylcellulose Sodium / chemistry*
  • Cyclodextrins / chemistry
  • Diabetes Mellitus / metabolism*
  • Drug Carriers / chemistry
  • Drug Liberation
  • Eugenol / chemistry*
  • Eugenol / pharmacology
  • Gene Expression Regulation / drug effects
  • Human Umbilical Vein Endothelial Cells / metabolism
  • Humans
  • Hydrogels / chemistry*
  • Inflammation / drug therapy*
  • Mice, Inbred C57BL
  • NF-kappa B / genetics
  • NF-kappa B / metabolism
  • Receptors, Lipoprotein / metabolism
  • Vascular Endothelial Growth Factor A / genetics
  • Vascular Endothelial Growth Factor A / metabolism
  • Wound Healing / drug effects*
  • beta-Cyclodextrins / chemistry*

Substances

  • Antioxidants
  • Cyclodextrins
  • Drug Carriers
  • Hydrogels
  • NF-kappa B
  • Receptors, Lipoprotein
  • Vascular Endothelial Growth Factor A
  • beta-Cyclodextrins
  • Eugenol
  • Carboxymethylcellulose Sodium