Whole-Genome Sequencing of an Uncommon Cryptococcus neoformans MLST43 Genotype Isolated in Nigeria

Mycopathologia. 2019 Oct;184(5):555-557. doi: 10.1007/s11046-019-00376-1. Epub 2019 Aug 31.

Abstract

Cryptococcosis is a human infection caused mainly by two species of the Cryptococcus genus, Cryptococcus neoformans and Cryptococcus gattii, whose populations contain several phylogenetically related haploid (VN/VG-types) and hybrid genotypes. Here, we report the whole-genome sequencing of a Nigerian C. neoformans VNII, Mat-α, strain with a rare multilocus-sequence-type (MLST) genotype (ST43).

Keywords: C. neoformans; Cryptococcosis; Cryptococcus; Next-generation sequencing; Whole-genome assembly.

MeSH terms

  • Cryptococcosis / microbiology*
  • Cryptococcus neoformans / classification
  • Cryptococcus neoformans / genetics*
  • Cryptococcus neoformans / isolation & purification
  • Genome, Fungal*
  • Genotype
  • Humans
  • Multilocus Sequence Typing
  • Mycological Typing Techniques
  • Nigeria
  • Whole Genome Sequencing*