Endometrial Mucinous Adenocarcinoma in a Bitch With Pyometra-A Case Report

Top Companion Anim Med. 2019 Sep:36:16-21. doi: 10.1053/j.tcam.2019.06.002. Epub 2019 Jun 25.

Abstract

Endometrial adenocarcinomas present rare neoplasia of bitches. This case report describes mucinous endometrial adenocarcinoma in a bitch with concurrent pyometra for the first time. A mass on the uterine stump was removed during surgery of a 13-year-old bitch with clinically suspected pyometra. Histopathology revealed mucinous endometrial adenocarcinoma. The tumor was classified according to human classification, responding to women's type I (endometrioid carcinoma). Immunohistochemistry showed a positive expression of estrogen receptor α, progesterone receptor, p53, and p16 gene, while vimentin was not expressed.

Keywords: bitch; histology; immunohistochemistry; mucinous uterine adenocarcinoma; ovarian remnant syndrome; pyometra.

Publication types

  • Case Reports

MeSH terms

  • Adenocarcinoma, Mucinous / pathology
  • Adenocarcinoma, Mucinous / surgery
  • Adenocarcinoma, Mucinous / veterinary*
  • Animals
  • Biomarkers, Tumor / genetics
  • Dog Diseases / pathology*
  • Dog Diseases / surgery
  • Dogs
  • Endometrial Neoplasms / pathology
  • Endometrial Neoplasms / surgery
  • Endometrial Neoplasms / veterinary*
  • Female
  • Immunohistochemistry
  • Pyometra / veterinary*

Substances

  • Biomarkers, Tumor