A variant in FTO gene shows association with histological ulceration in cutaneous melanoma

Eric Kalo; Canan Güvenç; Vivien Marasigan; Diether Lambrechts; Joost van den Oord; Marjan Garmyn

doi:10.1111/cup.13575

A variant in FTO gene shows association with histological ulceration in cutaneous melanoma

J Cutan Pathol. 2020 Jan;47(1):98-101. doi: 10.1111/cup.13575. Epub 2019 Sep 12.

Authors

Eric Kalo¹, Canan Güvenç¹, Vivien Marasigan¹, Diether Lambrechts^{2

3}, Joost van den Oord⁴, Marjan Garmyn¹

Affiliations

¹ Department of Dermatology, University Hospitals Leuven, Leuven, Belgium.
² Center for Cancer Biology, VIB, Leuven, Belgium.
³ Laboratory for Translational Genetics, Department of Human Genetics, KU Leuven, Leuven, Belgium.
⁴ Department of Imaging and Pathology, Translational Cell and Tissue Research, University Hospitals Leuven, Leuven, Belgium.

PMID: 31469442
DOI: 10.1111/cup.13575

No abstract available

Keywords: FTO; GWAS; genetic association; histological ulceration; melanoma; regression analysis; risk loci; rs12596638; single nucleotide polymorphism (SNP); susceptibility.

MeSH terms

Adolescent
Adult
Aged
Aged, 80 and over
Alpha-Ketoglutarate-Dependent Dioxygenase FTO / genetics*
Belgium / epidemiology
Case-Control Studies
Female
Genome-Wide Association Study / methods
Genotype
Histology
Humans
Male
Melanoma / genetics*
Melanoma, Cutaneous Malignant
Middle Aged
Neoplasm Staging / methods
Polymorphism, Single Nucleotide / genetics*
Skin Neoplasms / genetics
Skin Neoplasms / pathology*
Ulcer / pathology
Young Adult

Substances

Alpha-Ketoglutarate-Dependent Dioxygenase FTO
FTO protein, human