Symplastic hemangioma developing over an infantile hemangioma during propranolol treatment

Pediatr Dermatol. 2019 Nov;36(6):961-962. doi: 10.1111/pde.13960. Epub 2019 Aug 29.

Abstract

We describe a case of a 6-month-old female patient with a segmental, superficial, infantile hemangioma (IH) on the forehead being treated with propranolol 2 mg/kg/d for 5 months, who developed a symplastic hemangioma (SH) over the preexisting lesion, highlighting the need to consider SH in the differential diagnosis of vascular lesions arising over preexisting vascular anomalies in children.

Keywords: infantile hemangioma; propranolol; segmental hemangioma; symplastic hemangioma.

Publication types

  • Case Reports

MeSH terms

  • Female
  • Hemangioma / drug therapy
  • Hemangioma / pathology*
  • Humans
  • Infant
  • Neoplasms, Second Primary / pathology*
  • Propranolol / therapeutic use
  • Skin Neoplasms / drug therapy
  • Skin Neoplasms / pathology*
  • Vasodilator Agents / therapeutic use

Substances

  • Vasodilator Agents
  • Propranolol