Influence of intra-abdominal pressure on the amplitude of fluctuations of cerebral hemoglobin concentration in the respiratory band

Piotr Sawosz; Michal Kacprzak; Przemyslaw Pulawski; Magdalena Morawiec; Karolina Bejm; Magdalena Bielacz; Roman Maniewski; Adam Liebert; Wojciech Dabrowski

doi:10.1364/BOE.10.003434

Influence of intra-abdominal pressure on the amplitude of fluctuations of cerebral hemoglobin concentration in the respiratory band

Biomed Opt Express. 2019 Jun 19;10(7):3434-3446. doi: 10.1364/BOE.10.003434. eCollection 2019 Jul 1.

Authors

Piotr Sawosz¹, Michal Kacprzak¹, Przemyslaw Pulawski¹, Magdalena Morawiec¹, Karolina Bejm¹, Magdalena Bielacz², Roman Maniewski¹, Adam Liebert¹, Wojciech Dabrowski³

Affiliations

¹ Nalecz Institute of Biocybernetics and Biomedical Engineering Polish Academy of Sciences, Warsaw, Poland.
² Institute of Tourism and Recreation, State Vocational College of Szymon Szymonowicz, Zamosc, Poland.
³ Department of Anesthesiology and Intensive Therapy, Medical University of Lublin, Lublin, Poland.

Abstract

An intra-abdominal pressure (IAP) is correlated with cerebral perfusion, in a mechanism of reducing venous outflow. The elevated intra-abdominal pressure leads to an increase in the intracranial pressure and a decrease in the cerebral perfusion pressure. We studied the relationship between the IAP and the cerebral oxygenation with the use of the near infrared spectroscopy technique during a gynecological surgery. The changes in hemoglobin concentrations were analyzed in the time-frequency domain in the frequency band related to respiration. The measurements were carried out in 15 subjects who underwent laparoscopic surgery. During the laparoscopy, the intra-abdominal cavity was insufflated with CO₂, which caused a controlled increase in the IAP. It was observed that the amplitudes of respiration-related waves present in hemoglobin concentration signals show an increase of 1.5 to 8.5 times during elevation of the IAP by 15 mmHg.