Transfusion Management in Pediatric Oncology Patients

Marianne E Nellis; Ruchika Goel; Oliver Karam

doi:10.1016/j.hoc.2019.05.011

Transfusion Management in Pediatric Oncology Patients

Hematol Oncol Clin North Am. 2019 Oct;33(5):903-913. doi: 10.1016/j.hoc.2019.05.011. Epub 2019 Jul 5.

Authors

Marianne E Nellis¹, Ruchika Goel², Oliver Karam³

Affiliations

¹ Division of Pediatric Critical Care Medicine, Department of Pediatrics, NY Presbyterian Hospital - Weill Cornell Medicine, 525 East 68th Street, M-508, New York, NY 10065, USA. Electronic address: man9026@med.cornell.edu.
² Division of Hematology/Oncology, Simmons Cancer Institute at SIU School of Medicine, 315 West Carpenter Street, Springfield, IL 62702, USA; Department of Pathology, Johns Hopkins University, Baltimore, MD, USA. Electronic address: https://twitter.com/ruchika_goel1.
³ Division of Pediatric Critical Care Medicine, Department of Pediatrics, Children's Hospital of Richmond at VCU, 1250 East Marshall Street, Richmond, VA 23298, USA. Electronic address: https://twitter.com/DrOliverKaram.

PMID: 31466612
DOI: 10.1016/j.hoc.2019.05.011

Abstract

Pediatric oncology patients will likely require numerous transfusions of blood products, including red blood cell, platelet, and plasma transfusions, during the course of their treatment. Although strong evidence-based guidelines for these products in this patient population do not exist, given the morbidities associated with the receipt of blood products, practitioners should attempt to use restrictive transfusion strategies.

Keywords: Children; Oncology; Patient blood management; Transfusion.

Publication types

Review

MeSH terms

Blood Transfusion* / methods
Blood Transfusion* / standards
Child
Erythrocyte Transfusion
Hematologic Diseases / etiology*
Hematologic Diseases / therapy*
Humans
Leukocyte Transfusion
Medical Oncology / methods
Neoplasms / complications*
Platelet Transfusion