Transpancreatic mattress suture with Vicryl mesh around the stump decreases postoperative pancreatic fistula after distal pancreatectomy

J Hepatobiliary Pancreat Sci. 2019 Nov;26(11):510-516. doi: 10.1002/jhbp.664. Epub 2019 Sep 17.

Abstract

Background: Postoperative pancreatic fistula (POPF) after distal pancreatectomy (DP) remains the most common surgical complication. We have developed a novel stump closure technique after DP using transpancreatic mattress suture with Vicryl mesh (TMV) and reported our initial findings. The purpose of this study is to evaluate the efficacy of TMV compared to the conventional handsewn stump closure technique (CHS).

Methods: This retrospective single-center study included 165 consecutive patients who underwent open DP from January 2010 to May 2018. Of these, 71 patients underwent DP using TMV after September 2014 and 94 patients underwent DP with CHS. The surgical outcomes were compared between the two groups.

Results: Clinically relevant POPF rate in the TMV group was significantly lower than that in the CHS group (5.6% vs. 17.2%, P = 0.027). Morbidity rate was higher in the CHS group than that in the TMV group (16.9% vs. 27.7%, P = 0.104). In the multivariate analysis, absence of additional organ resection (OR 3.57; 95% CI 1.18-10.43; P = 0.025) and TMV (OR 0.24; 95% CI 0.07-0.73; P = 0.010) were identified as independent preventing factors for clinically relevant POPF.

Conclusion: TMV can be an effective stump closure technique for preventing POPF after DP.

Keywords: Distal pancreatectomy; Mattress suture; Postoperative pancreatic fistula; Stump closure; Vicryl mesh.

Publication types

  • Comparative Study

MeSH terms

  • Adult
  • Aged
  • Aged, 80 and over
  • Female
  • Humans
  • Male
  • Middle Aged
  • Pancreas / surgery*
  • Pancreatectomy / adverse effects*
  • Pancreatectomy / methods*
  • Pancreatic Diseases / surgery*
  • Pancreatic Fistula / etiology
  • Pancreatic Fistula / prevention & control*
  • Polyglactin 910 / administration & dosage*
  • Retrospective Studies
  • Suture Techniques*
  • Sutures
  • Young Adult

Substances

  • Polyglactin 910