Stereo- and Regioselective Synthesis of 4-Vinylpyrrolidine from N-Tethered Alkyne-Alkenol

Ngangbam Renubala Devi; Bipin K Behera; Anil K Saikia

doi:10.1021/acsomega.7b01785

Stereo- and Regioselective Synthesis of 4-Vinylpyrrolidine from N-Tethered Alkyne-Alkenol

ACS Omega. 2018 Jan 18;3(1):576-584. doi: 10.1021/acsomega.7b01785. eCollection 2018 Jan 31.

Authors

Ngangbam Renubala Devi¹, Bipin K Behera¹, Anil K Saikia¹

Affiliation

¹ Department of Chemistry, Indian Institute of Technology Guwahati, Guwahati 781039, India.

Abstract

Indium(III) chloride can be efficiently used for the synthesis of 4-vinylpyrrolidine from N-tethered alkyne-alkenol in good yields. The reaction is highly stereo- and regioselective.