Fetal tracheal occlusion for congenital diaphragmatic hernia

Semin Perinatol. 2020 Feb;44(1):151164. doi: 10.1053/j.semperi.2019.07.003. Epub 2019 Jul 30.

Abstract

Congenital diaphragmatic hernia (CDH) remains one of the most elusive birth defects to treat. Despite greater knowledge of disease and advances in technology, approximately one-third of CDH children born today still die. Consequently, clinicians and researchers have struggled to find the optimal treatment strategies for CDH. Without further innovations in postnatal treatment, many have focused an antenatal approach to improve pulmonary function. Fetoscopic Endoluminal Tracheal Occlusion (FETO) for CDH has evolved to the bedside after decades of research. While still under clinical investigation, FETO remains a promising adjunct to the treatment of CDH.

Keywords: Congenital diaphragmatic hernia; FETO; Fetal surgery; Tracheal occlusion.

Publication types

  • Review

MeSH terms

  • Female
  • Fetoscopy / methods*
  • Hernias, Diaphragmatic, Congenital / surgery*
  • Humans
  • Lung / abnormalities
  • Lung / growth & development*
  • Organ Size
  • Pregnancy
  • Prognosis
  • Severity of Illness Index
  • Trachea / surgery*
  • Treatment Outcome