Another step forward for methods for studying renal oxygenation

Kidney Int. 2019 Sep;96(3):552-554. doi: 10.1016/j.kint.2019.05.010.

Abstract

All available methods for assessing renal oxygenation are limited either in terms of their temporal or spatial resolution, their ability to quantify tissue oxygen tension (PO2), or in the settings in which they can be applied. Kodama and colleagues have developed a new method that utilizes dynamic nuclear polarization magnetic resonance imaging and an oxygen-sensitive paramagnetic agent (OX63). This new method generates quantitative maps of renal tissue PO2 in millimeters of mercury.

Publication types

  • Comment

MeSH terms

  • Animals
  • Diabetes Mellitus, Experimental*
  • Hypoxia
  • Kidney
  • Magnetic Resonance Imaging
  • Mice
  • Oxygen*

Substances

  • Oxygen