The novel HLA-C*04:387 allele is likely generated by intra-locus recombination event

HLA. 2019 Dec;94(6):535-537. doi: 10.1111/tan.13670. Epub 2019 Sep 8.

Authors

Won K Kwon¹, Sejun Hwang¹, So-Jung Choi², Eun-Suk Kang¹

Affiliations

¹ Department of Laboratory Medicine and Genetics, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, Korea.
² Field Application Specialist Department, Dow Biomedica Inc., Seoul, Korea.

PMID: 31444867
DOI: 10.1111/tan.13670

Abstract

The new HLA-C*04:387 allele was found and characterized in a Korean hematopoietic stem cell donor.

Keywords: HLA-C*04:387; human leukocyte antigen; novel allele; recombination.

© 2019 John Wiley & Sons A/S. Published by John Wiley & Sons Ltd.

Publication types

Case Reports

MeSH terms

Alleles
Asian People / genetics
Blood Donors
Female
Genetic Loci / genetics*
HLA-C Antigens / genetics*
Hematopoietic Stem Cell Transplantation
High-Throughput Nucleotide Sequencing
Histocompatibility Testing
Humans
Middle Aged
Polymorphism, Genetic*
Recombination, Genetic*
Republic of Korea
Sequence Analysis, DNA

Substances

HLA-C Antigens
HLA-C*04 antigen