Effect of quality control on the proliferation of the extract from Taraxacum mongolicum Hand.-Mazz. in Lactobacillus plantarum

Biomed Chromatogr. 2019 Dec;33(12):e4687. doi: 10.1002/bmc.4687. Epub 2019 Sep 8.

Abstract

In recent years, the fingerprint of high-performance liquid chromatography has been extensively applied in the identification and quality control of traditional Chinese medicine. It can be a potential protocol for assessing the authenticity, stability and consistency of traditional Chinese medicine and guaranteeing the expected biological activity. In this paper, a method using high-performance liquid chromatography to identify and control the quality of the extract of Taraxacum mongolicum Hand.-Mazz. (TME) was established. With this method, the correlation coefficients of the similarity of 10 batches were ≥0.994. The TME displayed a steady proliferative effect in Lactobacillus plantarum. In brief, this study successfully built a reliable, simple and efficient method to control and confirm the quality and the stability of biological activity of the TME.

Keywords: Taraxacum mongolicum hand.-Mazz.; fingerprint; high-performance liquid chromatography; lactobacillus plantarum; proliferation; similarity analysis.

MeSH terms

  • Cell Proliferation / drug effects*
  • Chromatography, High Pressure Liquid
  • Lactobacillus plantarum / drug effects*
  • Plant Extracts* / analysis
  • Plant Extracts* / chemistry
  • Plant Extracts* / pharmacology
  • Plant Extracts* / standards
  • Quality Control
  • Reproducibility of Results
  • Taraxacum / chemistry*

Substances

  • Plant Extracts