A Case of Primary Colonic Signet Ring Cell Carcinoma in a Young Man which Preoperatively Mimicked Phlebosclerotic Colitis

Acta Med Okayama. 2019 Aug;73(4):361-365. doi: 10.18926/AMO/56939.

Abstract

A 35-year-old man was referred to our hospital for chronic abdominal pain and diarrhea. Computed tomography showed wall thickening, poor contrast enhancement and calcification of the ascending colon, which were consistent with phlebosclerotic colitis. Malignant character was not detected from a biopsy specimen. Operatively, we observed a scirrhous mass of the ascending colon invading surrounding tissue, which was diagnosed as signet ring cell carcinoma based on analysis of an intraoperative frozen section. Right hemicolectomy with regional lymph node dissection was performed. This case was extremely similar to phlebosclerotic colitis in clinical findings; surgical resection was required for correct diagnosis.

Keywords: colorectal cancer; phlebosclerotic colitis; signet ring cell carcinoma; young colorectal cancer.

Publication types

  • Case Reports

MeSH terms

  • Adult
  • Carcinoma, Signet Ring Cell / diagnosis*
  • Carcinoma, Signet Ring Cell / pathology
  • Carcinoma, Signet Ring Cell / surgery
  • Colitis / diagnosis*
  • Colonic Neoplasms / diagnosis*
  • Colonic Neoplasms / pathology
  • Colonic Neoplasms / surgery
  • Humans
  • Male