Atrial Fibrillation and Diabetes Mellitus: JACC Review Topic of the Week

Allen Wang; Jennifer B Green; Jonathan L Halperin; Jonathan P Piccini Sr

doi:10.1016/j.jacc.2019.07.020

Atrial Fibrillation and Diabetes Mellitus: JACC Review Topic of the Week

J Am Coll Cardiol. 2019 Aug 27;74(8):1107-1115. doi: 10.1016/j.jacc.2019.07.020.

Authors

Allen Wang¹, Jennifer B Green², Jonathan L Halperin³, Jonathan P Piccini Sr⁴

Affiliations

¹ Duke Center for Atrial Fibrillation, Department of Medicine, Duke University Medical Center, Durham, North Carolina.
² Duke Clinical Research Institute, Durham, North Carolina.
³ Mount Sinai Hospital, New York, New York.
⁴ Duke Center for Atrial Fibrillation, Department of Medicine, Duke University Medical Center, Durham, North Carolina; Duke Clinical Research Institute, Durham, North Carolina. Electronic address: jonathan.piccini@duke.edu.

PMID: 31439220
DOI: 10.1016/j.jacc.2019.07.020

Abstract

Diabetes mellitus is one of the most common chronic medical conditions, and is a risk factor for the development of atrial fibrillation (AF). The presence of diabetes in patients with AF is associated with increased symptom burden and increased cardiovascular and cerebrovascular mortality. The pathophysiology of diabetes-related AF is not fully understood, but is related to structural, electrical, electromechanical, and autonomic remodeling. This paper reviews the complex interaction between diabetes and AF, and explores its effect on the prevention and treatment of AF.

Keywords: atrial fibrillation; diabetes mellitus.

Publication types

Research Support, Non-U.S. Gov't
Review

MeSH terms

Atrial Fibrillation / epidemiology*
Atrial Fibrillation / physiopathology*
Atrial Fibrillation / therapy
Atrial Remodeling / physiology
Cardiology / methods
Cardiology / standards*
Diabetes Mellitus / epidemiology*
Diabetes Mellitus / physiopathology*
Diabetes Mellitus / therapy
Humans
Risk Factors
United States / epidemiology