Carnival: A Graph-Based Data Integration and Query Tool to Support Patient Cohort Generation for Clinical Research

Stud Health Technol Inform. 2019 Aug 21:264:35-39. doi: 10.3233/SHTI190178.

Abstract

Clinical research studies often leverage various heterogeneous data sources including patient electronic health record, online survey, and genomic data. We introduce a graph-based, data integration and query tool called Carnival. We demonstrate its powerful ability to unify data from these disparate data sources to create datasets for two studies: prevalence and incidence case/control matches for coronary artery disease and controls for Marfan syndrome. We conclude with future directions for Carnival development.

Keywords: biomedical research; cohort studies; information storage and retrieval.

MeSH terms

  • Case-Control Studies
  • Cohort Studies
  • Data Analysis*
  • Electronic Health Records*
  • Humans
  • Information Storage and Retrieval*