Invasive left ventricle pressure-volume analysis: overview and practical clinical implications

Eur Heart J. 2020 Mar 21;41(12):1286-1297. doi: 10.1093/eurheartj/ehz552.

Abstract

Ventricular pressure-volume (PV) analysis is the reference method for the study of cardiac mechanics. Advances in calibration algorithms and measuring techniques brought new perspectives for its application in different research and clinical settings. Simultaneous PV measurement in the heart chambers offers unique insights into mechanical cardiac efficiency. Beat to beat invasive PV monitoring can be instrumental in the understanding and management of heart failure, valvular heart disease, and mechanical cardiac support. This review focuses on intra cardiac left ventricular PV analysis principles, interpretation of signals, and potential clinical applications.

Keywords: Left ventricular haemodynamics; Myocardial energetics; Pressure-volume loop.

Publication types

  • Research Support, Non-U.S. Gov't
  • Review

MeSH terms

  • Cardiac Volume
  • Heart
  • Heart Failure*
  • Heart Ventricles* / diagnostic imaging
  • Humans
  • Myocardial Contraction
  • Stroke Volume
  • Ventricular Function, Left
  • Ventricular Pressure