The preleukemic TCF3-PBX1 gene fusion can be generated in utero and is present in ≈0.6% of healthy newborns

Affiliations

• ¹ Department of Pediatric Oncology, Hematology and Clinical Immunology, University Children's Hospital, Medical Faculty, Heinrich Heine University Düsseldorf, Düsseldorf, Germany.
• ² Department of Pediatrics and Adolescent Medicine, The Juliane Marie Centre, Rigshospitalet, Copenhagen University Hospital and University of Copenhagen, Copenhagen, Denmark.
• ³ Department of Pediatrics, University Hospital Erlangen, Erlangen, Germany.
• ⁴ Rina Zaizov Pediatric Hematology Oncology Division, Schneider Children's Medical Center of Israel, Petach Tiqva, Israel; and.
• ⁵ The Dora and Gregorio Chair of Hematological Malignancies Department of Human Molecular Genetics and Biochemistry, Sackler School of Medicine, Tel Aviv University, Tel Aviv, Israel.