A new isoflavone glycoside from flowers of Pueraria Montana var. lobata (Willd.) Sanjappa & Pradeep

Nat Prod Res. 2021 May;35(9):1459-1464. doi: 10.1080/14786419.2019.1655021. Epub 2019 Aug 21.

Abstract

A new isoflavone glycoside, named 3'-hydroxytectorigenin-7-O-β-D-xylosyl-(1→6)-β-D-glucopyranoside (1) was isolated from the flowers of Pueraria montana var. lobata (Willd.) Sanjappa & Pradeep. The structure of compound 1 was characterised by HR-ESI-MS and NMR spectroscopic methods. In radical scavenging activity test using 2, 2-diphenyl-1-picrylhydrazyl (DPPH), compound 1 showed moderate activity with IC50 value of 42 ± 4.2 μg/mL.

Keywords: 3’-hydroxy -tectorigenin-7-O-β-D-xylosyl-(1→6)-β-D-glucopyranoside; Pueraria montana var. lobata; isoflavone glycoside; radical scavenging activity.

MeSH terms

  • Biphenyl Compounds / chemistry
  • Flowers / chemistry*
  • Free Radical Scavengers / chemistry
  • Glycosides / chemistry
  • Glycosides / isolation & purification*
  • Inhibitory Concentration 50
  • Isoflavones / chemistry
  • Isoflavones / isolation & purification*
  • Picrates / chemistry
  • Pueraria / chemistry*

Substances

  • Biphenyl Compounds
  • Free Radical Scavengers
  • Glycosides
  • Isoflavones
  • Picrates
  • 1,1-diphenyl-2-picrylhydrazyl