Comparative finite element modelling of aneurysm formation and physiologic inflation in the descending aorta

Comput Methods Biomech Biomed Engin. 2019 Nov;22(15):1197-1208. doi: 10.1080/10255842.2019.1650036. Epub 2019 Aug 21.

Abstract

Despite the general interest in aneurysm rupture prediction, the aneurysm formation has received limited attention. The goal of this study is to assess whether an aneurysm may be instigated in a healthy model of an aorta inflated by a supra-physiological pressure. The effect of two main aspects on numerical predictions has been explored: i) the geometric design and ii) the constitutive law adopted to represent the material properties. Firstly, higher values of wall stress and displacement magnitude were generated in the physiologic model compared to the cylindrical one when assigning the same material properties. Secondly, greater deformations are observed in the anisotropic model compared to the isotropic one.

Keywords: Fung; aneurysm; anisotropic; aorta; finite element.

Publication types

  • Comparative Study

MeSH terms

  • Aneurysm / physiopathology*
  • Anisotropy
  • Aorta, Thoracic / physiopathology*
  • Biomechanical Phenomena
  • Finite Element Analysis*
  • Humans
  • Models, Cardiovascular*
  • Pressure
  • Stress, Mechanical