Rhodol-based fluorescent probes for the detection of fluoride ion and its application in water, tea and live animal imaging

Spectrochim Acta A Mol Biomol Spectrosc. 2020 Jan 5:224:117467. doi: 10.1016/j.saa.2019.117467. Epub 2019 Aug 11.

Abstract

Herein, we presented two novel turn-on colorimetric and fluorescent probes based on a F- triggered SiO bond cleavage reaction, which displayed several desired properties for the quantitative detection for F-, such as high specificity, rapid response time (within 3 min) and naked-eye visualization. The fluorescence intensity at 574 nm (absorbance at 544 nm) of the solution was found to increase linearly with the concentration of F- (0.00-30.0 μM) with the detection limit was estimated to be 0.47 μM/0.48 μM. Based on these excellent optical properties, the probes were employed to monitor F- in real water samples and tea samples with satisfactory. Furthermore, it was successfully applied for fluorescent imaging of F- in living nude mice, suggesting that it could be used as a powerful tool to predict and explore the biological functions of F- in physiological and pathological processes.

Keywords: Bioimaging; Fluorescent; Fluoride ion; Seminaphthorhodafluor dye; Tea samples.

MeSH terms

  • Animals
  • Colorimetry
  • Fluorescent Dyes / chemistry*
  • Fluorides / analysis*
  • Limit of Detection
  • Linear Models
  • Mice
  • Mice, Nude
  • Optical Imaging / methods*
  • Spectrometry, Fluorescence / methods*
  • Tea / chemistry
  • Water / chemistry
  • Xanthones / chemistry*

Substances

  • Fluorescent Dyes
  • Tea
  • Xanthones
  • rhodol
  • Water
  • Fluorides