A case of compound heterozygous hemoglobin Köln/hemoglobin E in an Indian family

Pediatr Hematol Oncol. 2019 Sep;36(6):394-398. doi: 10.1080/08880018.2019.1648620. Epub 2019 Aug 19.

Abstract

Hemoglobin Köln, is the most common unstable hemoglobin variant worldwide, yet has only rarely been reported in Indians. Herein we report a case of coinheritance of Hb Köln and Hb E, which to the best of our knowledge has not been reported in the literature so far. The patient presented with mild symptoms of hemolysis with no previous history of blood transfusions.

Keywords: Hemoglobin Köln; hemoglobin E; unstable hemoglobin.

Publication types

  • Case Reports
  • Letter

MeSH terms

  • Child, Preschool
  • Hemoglobin E / genetics*
  • Hemoglobins, Abnormal / genetics*
  • Humans
  • India
  • Male

Substances

  • Hemoglobins, Abnormal
  • Hemoglobin E
  • hemoglobin Koln