The Editor has retracted this article [Iwamoto J, Sato Y, Uzawa M, Takeda T, Matsumoto H. Three-year Experience with Alendronate Treatment in Postmenopausal Osteoporotic Japanese Women with or without Renal Dysfunction: A Retrospective Study. Drugs Aging 2012; 29(2): 133-142.]. After publication, serious concerns were raised with respect to the reporting of the study design, methodology, data and authorship, and the Editor no longer has confidence in this article. Hideo Matsumoto and Tsuyoshi Takeda agree with this retraction. Jun Iwamoto and Mitsuyoshi Uzawa have not responded to correspondence about this retraction. Yoshihiro Sato is deceased.