The present study was designed to assess the influence of geographical factors on essential oil (EO) composition, along with antiradical potential and phytochemical contents of Ferulago angulata (Schltdl.) Boiss (Apiaceae) extracts for the first time. The aerial parts were hydrodistilled by Clevenger apparatus and subjected to gas chromatography coupled with flame ionization detector (GC/FID) and mass spectroscopy (GC/MS). The EO yields were significantly different from populations 'Mongar' (south-slope, 3000 m) with 1.34±0.06 % and 'Male-Amiri' (north slope, 2600 m) with 0.18±0.05 % of total oil. Thirty-nine compounds were identified from the EOs of nine populations. α-Pinene was the predominant component ranging from 20.84 to 49.06 % in 'Gandomkar' (north-slope, 2500 m) and 'Mongar' (3000 m), respectively. The methanolic extract of 'Mongar' (north-slope at 2500 m) possessed the highest total phenolic contents. Also, this population logically exhibited potent antiradical activity using both 1,1-diphenyl-2-picrylhydrazyl (DPPH) and oxygen radical absorbance capacity (ORAC) assays with EC50 of 42.07±4.12 μg/mL and 8.34±0.21 mmol Trolox® equivalents/g, respectively. Due to its moderate free-radical scavenging potential and high α-pinene content, the population 'Mongar' might be considered as a perspective raw material in food and phytopharmaceutical industries.
Keywords: Apiaceae; Ferulago angulata; antiradical potential; chemo-diversity; ecological impacts.
© 2019 The Authors. Published by Wiley-VHCA AG, Zurich, Switzerland.