Successful Pregnancy of a Patient with Cystic Fibrosis Genotype F508del/ F508del and Progressed Pulmonary Destruction on lumacaftor/ivacaftor

Klin Padiatr. 2019 Sep;231(5):271-273. doi: 10.1055/a-0973-8565. Epub 2019 Aug 13.

Authors

Jochen G Mainz^{1

2}, Ruth Katharina Michl¹, Natalie Beiersdorf¹, Michael Lorenz¹, Uwe Schneider³, Tanja Groten³, Anke Jaudszus¹

Affiliations

¹ Cystic Fibrosis Centre / Ped. Pneumology, University of Jena, Jena, Germany.
² Pediatric Pulmonology / Cystic Fibrosis, Brandenburg Medical School (MHB), Brandenburg an der Havel, Germany.
³ Obstetrics, University of Jena, Jena, Germany.

PMID: 31408905
DOI: 10.1055/a-0973-8565

No abstract available

Publication types

Case Reports

MeSH terms

Adult
Aminophenols / therapeutic use*
Aminopyridines / therapeutic use*
Benzodioxoles / therapeutic use*
Cystic Fibrosis / complications
Cystic Fibrosis / diagnosis
Cystic Fibrosis / drug therapy*
Cystic Fibrosis / genetics
Cystic Fibrosis Transmembrane Conductance Regulator / genetics
Female
Genotype
Humans
Lung / physiopathology
Mutation
Pregnancy
Pregnancy Outcome*
Quinolones / therapeutic use*

Substances

Aminophenols
Aminopyridines
Benzodioxoles
Quinolones
cystic fibrosis transmembrane conductance regulator delta F508
Cystic Fibrosis Transmembrane Conductance Regulator
ivacaftor
lumacaftor