Sudden unexpected death in Parkinson's disease: why is drinking water important?

Neurodegener Dis Manag. 2019 Aug;9(4):241-246. doi: 10.2217/nmt-2019-0010. Epub 2019 Aug 13.

Abstract

Parkinson's disease (PD) is one of the most common age-related neurodegenerative disorders. Several studies over the last few years have shown that PD is accompanied by high rates of premature death compared with healthy controls. Death in PD patients is usually caused by determinant factors such as pneumonia, and cerebrovascular and cardiovascular diseases. During recent years it has emerged that dehydration may also contribute to mortality in PD. Interestingly, it has been documented that a substantial proportion of patients with PD die suddenly (known as sudden and unexpected death in PD). In this article, we focus on the magnitude of the problem of sudden and unexpected death in PD, with special reference to the daily water consumption of PD patients.

Keywords: Parkinson’s disease; dehydration; elderly; sudden death; water consumption.

Publication types

  • Research Support, Non-U.S. Gov't
  • Review

MeSH terms

  • Antiparkinson Agents / adverse effects
  • Antiparkinson Agents / therapeutic use
  • Death, Sudden / etiology*
  • Deglutition Disorders / etiology
  • Dehydration / complications*
  • Dehydration / therapy
  • Drinking Behavior*
  • Fluid Therapy
  • Humans
  • Neuroleptic Malignant Syndrome / etiology
  • Neuroleptic Malignant Syndrome / prevention & control
  • Parkinson Disease / complications*
  • Parkinson Disease / mortality
  • Patient Compliance
  • Water*
  • Water-Electrolyte Balance
  • Water-Electrolyte Imbalance / etiology

Substances

  • Antiparkinson Agents
  • Water