Diversity of potentially exploitable pharmacological activities of the highly prized edible medicinal fungus Antrodia camphorata

Appl Microbiol Biotechnol. 2019 Oct;103(19):7843-7867. doi: 10.1007/s00253-019-10016-9. Epub 2019 Aug 12.

Abstract

Antrodia camphorata, also known as A. cinnamomea, is a precious medicinal basidiomycete fungus endemic to Taiwan. This article summarizes the recent advances in research on the multifarious pharmacological effects of A. camphorata. The mushroom exhibits anticancer activity toward a large variety of cancers including breast, cervical, ovarian, prostate, bladder, colorectal, pancreatic, liver, and lung cancers; melanoma; leukemia; lymphoma; neuroblastoma; and glioblastoma. Other activities encompass antiinflammatory, antiatopic dermatitis, anticachexia, immunoregulatory, antiobesity, antidiabetic, antihyperlipidemic, antiatherosclerotic, antihypertensive, antiplatelet, antioxidative, antiphotodamaging, hepatoprotective, renoprotective, neuroprotective, testis protecting, antiasthmatic, osteogenic, osteoprotective, antiviral, antibacterial, and wound healing activities. This review aims to provide a reference for further development and utilization of this highly prized mushroom.

Keywords: Anticancer; Antiinflammatory; Antileukemia; Antrodia camphorata; Hepatoprotective; Neuroprotective.

Publication types

  • Review

MeSH terms

  • Antrodia / classification*
  • Antrodia / genetics
  • Antrodia / metabolism*
  • Biological Products / metabolism*
  • Genetic Variation*
  • Taiwan
  • Technology, Pharmaceutical / methods*

Substances

  • Biological Products