[Successful treatment of unresectable advanced gastric cancer with bladder metastasis using mFOLFOX6:a case report]

Nihon Shokakibyo Gakkai Zasshi. 2019;116(8):676-684. doi: 10.11405/nisshoshi.116.676.
[Article in Japanese]

Abstract

A 42-year-old woman was referred to our hospital for the treatment of pyloric stenosis. Esophagogastroduodenoscopy (EGD) and computed tomography (CT) revealed the presence of type 4 advanced gastric cancer with bladder metastasis and peritoneal dissemination. Biopsy specimen examination revealed poorly differentiated adenocarcinoma with signet ring cell carcinoma. Thus, two cycles of chemotherapy with 5-fluorouracil, leucovorin, and oxaliplatin were administered. Subsequently, the gastric lesion and bladder metastasis reduced as detected using EGD and CT. Consequently, she achieved adequate oral intake. After changing the regimen to tegafur/gimeracil/oteracil and oxaliplatin, she was discharged. Currently, she continues to receive chemotherapy.

Publication types

  • Case Reports

MeSH terms

  • Adult
  • Antineoplastic Combined Chemotherapy Protocols / therapeutic use*
  • Female
  • Humans
  • Leucovorin / therapeutic use
  • Organoplatinum Compounds / therapeutic use
  • Stomach Neoplasms / diagnosis*
  • Stomach Neoplasms / therapy
  • Urinary Bladder / pathology
  • Urinary Bladder Neoplasms / secondary*
  • Urinary Bladder Neoplasms / therapy

Substances

  • Organoplatinum Compounds
  • Leucovorin