Sclerosing mucoepidermoid carcinoma with eosinophilia of thyroid

BMJ Case Rep. 2019 Aug 8;12(8):e225685. doi: 10.1136/bcr-2018-225685.

Abstract

Sclerosing mucoepidermoid carcinoma of the thyroid was first reported in 1991. This tumour type may develop as associated to Hashimoto thyroiditis. There are two variants of mucoepidermoid carcinoma of thyroid. The conventional and the sclerosing variants. Sclerosing mucoepidermoid carcinoma with eosinophilia of thyroid (SCME) has recently been recognised as a separate disease entity by the WHO. We report a case of SCME in a 62-year-old male patient who presented with a painless anterior neck swelling. Total thyroidectomy was performed, and no adjuvant treatment administered. The patient remained disease free up until 10 months of follow-up. Approximately 40 cases are reported in literature. We report the second case of SCME in Asian men. Sclerosing mucoepidermoid carcinoma with eosinophilia of thyroid should be differentiated from the conventional mucoepidermoid carcinoma. Patients should also be advised of long-term follow-up for surveillance.

Keywords: ear, nose and throat/otolaryngology; thyroid disease.

Publication types

  • Case Reports

MeSH terms

  • Biopsy, Fine-Needle
  • Carcinoma, Mucoepidermoid / diagnosis
  • Carcinoma, Mucoepidermoid / pathology*
  • Carcinoma, Mucoepidermoid / surgery
  • Eosinophilia / pathology
  • Humans
  • Male
  • Middle Aged
  • Thyroid Neoplasms / diagnosis
  • Thyroid Neoplasms / pathology*
  • Thyroid Neoplasms / surgery
  • Thyroidectomy