Cellular Organization: Bulk Actin Network Flows Drive Ooplasm Segregation

Niv Ierushalmi; Kinneret Keren

doi:10.1016/j.cub.2019.06.063

Cellular Organization: Bulk Actin Network Flows Drive Ooplasm Segregation

Curr Biol. 2019 Aug 5;29(15):R758-R761. doi: 10.1016/j.cub.2019.06.063.

Authors

Niv Ierushalmi¹, Kinneret Keren²

Affiliations

¹ Department of Physics, Technion - Israel Institute of Technology, Haifa 32000, Israel.
² Department of Physics, Technion - Israel Institute of Technology, Haifa 32000, Israel; Network Biology Research Laboratories and Russell Berrie Nanotechnology Institute, Technion - Israel Institute of Technology, Haifa 32000, Israel. Electronic address: kinneret@physics.technion.ac.il.

PMID: 31386856
DOI: 10.1016/j.cub.2019.06.063

Abstract

Actin networks in the bulk cytoplasm, rather than cortical dynamics, drive ooplasm segregation in zebrafish oocytes. A contracting actin network drags the ooplasm toward the animal pole, while 'comet tails' push the yolk granules in the opposite direction.

Publication types

Comment

MeSH terms

Actins*
Animals
Cytoplasm
Oocytes
Zebrafish*

Substances

Actins