A minireview of hydroamination catalysis: alkene and alkyne substrate selective, metal complex design

BMC Chem. 2019 Jul 11;13(1):89. doi: 10.1186/s13065-019-0606-7. eCollection 2019 Dec.

Abstract

Organic compounds that contain nitrogen are very important intermediates in pharmaceutical and chemical industry. Hydroamination is the reaction that can form C-N bond with high atom economy. The research progress in metals catalyzed hydroamination of alkenes and alkynes from the perspective of reaction mechanism is categorized and summarized.

Keywords: Atom economy; C–N bond; Hydroamination; Metal catalysis.

Publication types

  • Review