Acute kidney injury associated with lymphangitic carcinomatosis

Clin Kidney J. 2018 Oct 10;12(4):527-529. doi: 10.1093/ckj/sfy099. eCollection 2019 Aug.

Abstract

Acute kidney injury (AKI) is a major complication in patients with cancer, associated with significant morbidity and mortality. Only two cases of kidney lymphangitic carcinomatosis associated with AKI have been reported, in gastric and colorectal adenocarcinoma. Here, we report on a 53-year-old man with pancreatic adenocarcinoma who developed AKI as a result of kidney lymphangitic carcinomatosis. The patient rapidly became anuric and required haemodialysis. Kidney lymphangitic carcinomatosis should be considered as a cause of AKI in patients with cancer and may become a more frequent clinical finding as patients with metastatic carcinoma survive for longer.

Keywords: acute kidney injury; cancer; immunohistochemistry; kidney biopsy; lymphangitic carcinomatosis.