Direct-from-Specimen Pathogen Identification: Evolution of Syndromic Panels

Marc Roger Couturier; Jennifer Dien Bard

doi:10.1016/j.cll.2019.05.005

Direct-from-Specimen Pathogen Identification: Evolution of Syndromic Panels

Clin Lab Med. 2019 Sep;39(3):433-451. doi: 10.1016/j.cll.2019.05.005.

Authors

Marc Roger Couturier¹, Jennifer Dien Bard²

Affiliations

¹ ARUP Laboratories, University of Utah, 500 Chipeta Way, Salt Lake City, UT 84108, USA. Electronic address: marc.couturier@aruplab.com.
² Microbiology and Virology Laboratories, Department of Pathology and Laboratory Medicine, Children's Hospital Los Angeles, University of Southern California, 4650 Sunset Boulevard MS#32, Los Angeles, CA 90027, USA.

Abstract

This article describes the current state of the art with regards to commercially available syndromic panels for blood stream infections, gastrointestinal pathogen detection, respiratory tract infections, and central nervous system infections, while providing a provocative and speculative look into the future of syndromic panel testing for infectious diseases.

Keywords: Encephalitis panel; Gastroenteritis panel; Meningitis panel; Respiratory panel; Sepsis panel; Syndromic panel.

Publication types

Review

MeSH terms

Communicable Diseases / diagnosis*
Humans
Microbiological Techniques / methods*
Molecular Diagnostic Techniques
Specimen Handling*