Inflammatory bowel disease: Looking beyond the tract

Int J Immunopathol Pharmacol. 2019 Jan-Dec:33:2058738419866567. doi: 10.1177/2058738419866567.

Abstract

Inflammatory bowel disease is a chronic inflammatory condition that encompasses Crohn's disease and ulcerative colitis. Inflammatory bowel disease is not exclusive to the gastrointestinal system, as it has been identified to be associated with extraintestinal manifestations that encompass every other organ system in the human body. This review article will comprehensively review the current knowledge on extraintestinal manifestations of inflammatory bowel disease. In addition, it will discuss the recommendations for screening and surveillance for extraintestinal manifestations in these patients since early appropriate diagnosis is imperative in preventing morbidity and cancer development.

Keywords: Crohn’s disease; extraintestinal manifestations; inflammatory bowel disease; screening; treatment; ulcerative colitis.

Publication types

  • Review

MeSH terms

  • Colitis, Ulcerative / diagnosis
  • Crohn Disease / diagnosis
  • Humans
  • Inflammation / diagnosis
  • Inflammatory Bowel Diseases / diagnosis*