Young Vasospastic Angina Patients Less Than 20 Years Old

Circ J. 2019 Aug 23;83(9):1925-1928. doi: 10.1253/circj.CJ-19-0433. Epub 2019 Aug 2.

Abstract

Background: Japanese Circulation Society (JCS) guidelines do not include adolescents with coronary artery spasm.Methods and Results:We recruited 18 adolescents less than 20 years old with vasospastic angina (VSA): 11 were Japanese and 3 had chest symptoms for >12 months before admission. ST-segment elevation was observed in 11 patients and none of the 18 patients had a fixed stenosis. Spasm provocation tests were performed in 9 patients and two-thirds had multiple spasms; 6 suffered from acute myocardial infarction and ventricular fibrillation occurred in 2 patients; 1 patient died and the remaining 17 patents survived.

Conclusions: Clinical status of adolescents with VSA was as severe as in adults with refractory VSA. Cardiologists should cooperate with pediatricians to diagnose and treat adolescents with VSA. There is a need to establish the additional issues for adolescents with coronary spasm in the JCS guidelines.

Keywords: Adolescents; Cardiologists; Guidelines; Pediatricians; Vasospastic angina.

Publication types

  • Review

MeSH terms

  • Adolescent
  • Age of Onset
  • Angina Pectoris / complications
  • Angina Pectoris / diagnosis
  • Angina Pectoris / drug therapy
  • Angina Pectoris / physiopathology*
  • Angina Pectoris, Variant
  • Child
  • Coronary Vasospasm / complications
  • Coronary Vasospasm / diagnosis
  • Coronary Vasospasm / drug therapy
  • Coronary Vasospasm / physiopathology*
  • Coronary Vessels / diagnostic imaging
  • Coronary Vessels / drug effects
  • Coronary Vessels / physiopathology*
  • Female
  • Humans
  • Male
  • Myocardial Infarction / etiology
  • Myocardial Infarction / physiopathology
  • Prognosis
  • Risk Factors
  • Vasoconstriction* / drug effects
  • Vasodilator Agents / therapeutic use
  • Ventricular Fibrillation / etiology
  • Ventricular Fibrillation / physiopathology

Substances

  • Vasodilator Agents