Pharmacokinetic-pharmacodynamic modeling of cyadox against Escherichia coli in swine

Microb Pathog. 2019 Oct:135:103650. doi: 10.1016/j.micpath.2019.103650. Epub 2019 Jul 31.

Authors

Lingli Huang¹, Muhammad Kashif Maan¹, Dongting Xu¹, Muhammad Abu Bakr Shabbir¹, Menghong Dai¹, Zonghui Yuan²

Affiliations

¹ National Reference Laboratory of Veterinary Drug Residues/ MAO Key Laboratory for the Detection of Veterinary Drug Residues, Huazhong Agricultural University, Wuhan, 430070, PR China.
² National Reference Laboratory of Veterinary Drug Residues/ MAO Key Laboratory for the Detection of Veterinary Drug Residues, Huazhong Agricultural University, Wuhan, 430070, PR China. Electronic address: yuan5802@mail.hzau.edu.cn.

PMID: 31376503
DOI: 10.1016/j.micpath.2019.103650

No abstract available

Keywords: Cyadox; Dose optimization; Escherichia coli; PK/PD; Pig.

MeSH terms

Animals
Anti-Bacterial Agents / administration & dosage
Anti-Bacterial Agents / blood
Anti-Bacterial Agents / pharmacokinetics*
Escherichia coli / drug effects*
Escherichia coli / physiology
Escherichia coli Infections / microbiology
Escherichia coli Infections / veterinary*
Female
Ileum / microbiology
Male
Microbial Sensitivity Tests
Models, Biological
Quinoxalines / administration & dosage
Quinoxalines / blood
Quinoxalines / pharmacokinetics
Swine
Swine Diseases / drug therapy*
Swine Diseases / microbiology

Substances

Anti-Bacterial Agents
Quinoxalines
cyadox