Functional lymphatic reconstruction with the "Selected Lymph Node" technique guided by a SPECT-CT lymphoscintigraphy

J Surg Oncol. 2019 Nov;120(6):911-918. doi: 10.1002/jso.25650. Epub 2019 Aug 2.

Abstract

Background: A new technique named "Selected Lymph Node" ("SeLyN") was evaluated, aiming to identify the most functional groin lymph nodes (LNs) for an effective LN transplantation.

Methods: Bilateral lower-limb SPECT-CT was performed in the upper-limb lymphedema patients, to select the most radioactive inguinal LN. Recorded data included demographics, stage, etiology of lymphedema, flap consistency in accordance to preoperative findings, flap size, number of LN, and harvesting time. Infection episodes per year and volume changes of the upper limbs were documented. Donor-site complications were recorded and lower-limb evaluation was performed through clinical examination, volume analysis, and lymphoscintigraphy.

Results: A total of 41 patients underwent a "SeLyN" transfer technique. The mean flap size was 28.34 cm2 containing a mean of 3.4 LNs. The mean time spent on flap harvest was 39 minutes. A mean 56.5% volume reduction (P < .001) and a mean 1.41 to 0.29 infection episodes per patient per year (P < .001) were recorded. Clinical evaluation and lymphography of the donor site advocated no major complications for a mean follow-up period of 42.5 months.

Conclusions: "SeLyN" is a safe and effective technique in selecting the most suitable LNs, minimizing the donor-site morbidity, and decreasing the overall operating time.

Keywords: Selected Lymph Node; functional lymphatic reconstruction; groin lymph nodes; lymph node transplantation; lymphedema.

MeSH terms

  • Adult
  • Aged
  • Breast Neoplasms / pathology
  • Breast Neoplasms / surgery*
  • Female
  • Follow-Up Studies
  • Groin / surgery*
  • Humans
  • Lymph Nodes / diagnostic imaging
  • Lymph Nodes / transplantation*
  • Lymphatic Vessels / surgery*
  • Lymphedema / diagnostic imaging
  • Lymphedema / etiology
  • Lymphedema / surgery*
  • Lymphoscintigraphy / methods*
  • Male
  • Mastectomy / adverse effects
  • Middle Aged
  • Plastic Surgery Procedures / methods*
  • Prognosis
  • Retrospective Studies
  • Tomography, Emission-Computed, Single-Photon / methods
  • Tomography, X-Ray Computed / methods