Precision Medicine for Insomnia

Sleep Med Clin. 2019 Sep;14(3):291-299. doi: 10.1016/j.jsmc.2019.04.001. Epub 2019 Jun 5.

Abstract

Insomnia affects up to 15% of the US population. There are effective pharmacologic and behavioral treatments for insomnia; however, there is often no one-size-fits-all intervention. This article discusses the leading behavioral treatment of insomnia, cognitive behavioral therapy for insomnia, and its ability to be tailored to an individual's specific symptoms. It then discusses pharmacologic options for treating insomnia, and offers some guidance on medication selection to enhance personalized care. In addition, it discusses how the current evidence base can help providers make choices between pharmacologic and behavioral treatments.

Keywords: Behavioral treatment; CBT-I; Case conceptualization; Insomnia; Pharmacotherapy; Precision medicine; Sleep disturbance.

Publication types

  • Review

MeSH terms

  • Cognitive Behavioral Therapy*
  • Humans
  • Precision Medicine*
  • Sleep Aids, Pharmaceutical / therapeutic use*
  • Sleep Initiation and Maintenance Disorders / therapy*
  • Treatment Outcome

Substances

  • Sleep Aids, Pharmaceutical