Connecting the dots in type 1 diabetes: The role for gut-pancreas axis

J Leukoc Biol. 2019 Sep;106(3):501-503. doi: 10.1002/JLB.3CE0719-242R. Epub 2019 Aug 1.

Abstract

Discussion on changes in gut microbiota driving the breakdown of mucosal barrier in NOD mice; the resulting inflammation and impairment of oral tolerance induces the autoimmune diabetes.

Publication types

  • Editorial
  • Research Support, Non-U.S. Gov't
  • Comment

MeSH terms

  • Animals
  • Diabetes Mellitus, Experimental*
  • Diabetes Mellitus, Type 1*
  • Gastrointestinal Microbiome*
  • Mice
  • Mice, Inbred NOD
  • Mucous Membrane