Characterization of the novel HLA-DQA1*01:27 allele by sequencing-based typing

HLA. 2019 Oct;94(4):392-393. doi: 10.1111/tan.13647. Epub 2019 Aug 12.

Abstract

HLA-DQA1*01:27 differs from HLA-DQA1*01:01:01:01 by one nucleotide substitution in codon 221 in exon 4.

Keywords: HLA-DQA1*01:27; human leukocyte antigen; novel allele; sequencing-based typing.

MeSH terms

  • Alleles*
  • Arginine
  • Bone Marrow
  • Bone Marrow Transplantation
  • Exons
  • HLA-DQ alpha-Chains / genetics*
  • High-Throughput Nucleotide Sequencing
  • Histidine
  • Humans

Substances

  • HLA-DQ alpha-Chains
  • HLA-DQA1 antigen
  • Histidine
  • Arginine