Stereotactic radiosurgery for intracranial IgG4-related disease

J Med Imaging Radiat Oncol. 2019 Oct;63(5):707-710. doi: 10.1111/1754-9485.12931. Epub 2019 Aug 1.

Abstract

We report the case of a 20-year-old woman with intracranial IgG4-related disease, initially misdiagnosed as a meningioma on biopsy and treated with radiosurgery as it was in an eloquent location and not resectable. Her intracranial IgG4 disease had a near-complete response to radiosurgery and is still controlled six years later, so this case represents what we believe to be the first reported use of radiotherapy in the treatment of intracranial IgG4-related disease.

Keywords: IgG4; intracranial; radiation oncology; radiosurgery; stereotactic.

Publication types

  • Case Reports

MeSH terms

  • Brain Diseases / diagnosis
  • Brain Diseases / radiotherapy*
  • Diagnosis, Differential
  • Female
  • Humans
  • Immunoglobulin G4-Related Disease / diagnosis
  • Immunoglobulin G4-Related Disease / radiotherapy*
  • Magnetic Resonance Imaging
  • Radiosurgery / methods*
  • Young Adult