Subtype-specific differences in the risk of hospitalisation among patients infected with hepatitis E virus genotype 3 in Belgium, 2010-2018

Epidemiol Infect. 2019 Jan:147:e224. doi: 10.1017/S0950268819001122.

Abstract

Some European countries recently reported an increase in hepatitis E virus genotype 3 (HEV-3) of the subtype 3c. No link between HEV-3 subtypes and severity is established to date. Here, we report that patients infected with HEV-3c were at lower risk of hospitalisation, compared to those infected with HEV-3f, the other main subtype circulating in Belgium.

Keywords: Food-borne infections; hepatitis; infectious disease epidemiology; molecular epidemiology; zoonotic foodborne diseases.

Publication types

  • Comparative Study

MeSH terms

  • Adult
  • Age Factors
  • Aged
  • Animals
  • Belgium / epidemiology
  • Confidence Intervals
  • Female
  • Genotype
  • Hepatitis E / epidemiology*
  • Hepatitis E / genetics*
  • Hepatitis E / physiopathology
  • Hepatitis E virus / classification
  • Hepatitis E virus / genetics*
  • Hepatitis E virus / isolation & purification*
  • Hospital Mortality*
  • Hospitalization / statistics & numerical data
  • Humans
  • Male
  • Middle Aged
  • Phylogeny
  • Prevalence
  • Registries*
  • Retrospective Studies
  • Risk Assessment
  • Sex Factors
  • Survival Rate
  • Swine
  • Swine Diseases / epidemiology
  • Swine Diseases / virology