Achievements in Cancer Research and its Therapeutics in Hundred Years

Curr Top Med Chem. 2019;19(17):1545-1562. doi: 10.2174/1568026619666190730093034.

Abstract

Cancer research has progressed leaps and bounds over the years. This review is a brief overview of the cancer research, milestone achievements and therapeutic studies on it over the one hundred ten years which would give us an insight into how far we have come to understand and combat this fatal disease leading to millions of deaths worldwide. Modern biology has proved that cancer is a very complex disease as still we do not know precisely how it triggers. It involves several factors such as protooncogene, oncogene, kinase, tumor suppressor gene, growth factor, signalling cascade, micro RNA, immunity, environmental factors and carcinogens. However, modern technology now helps the cancer patient on the basis of acquired and established knowledge in the last hundred years to save human lives.

Keywords: Anti-cancer; Cancer; Drug Target; Drug discovery; Medicinal Chemistry; Oncogene; Therapeutics; Tumour..

Publication types

  • Historical Article
  • Review

MeSH terms

  • History, 20th Century
  • History, 21st Century
  • Humans
  • Neoplasms / drug therapy*
  • Neoplasms / genetics
  • Neoplasms / history*