Physiologic Uterine Uptake of Radioiodine During Menstruation Demonstrated by SPECT/CT

Clin Nucl Med. 2019 Dec;44(12):975-977. doi: 10.1097/RLU.0000000000002754.

Abstract

A 35-year-old woman with papillary thyroid cancer underwent I therapy after thyroidectomy. Post-therapy whole body scan revealed increased activity in the pelvis, in addition to the activity in the neck. On SPECT/CT images, the radioactivity in the pelvis was localized in the rectum and cervix. Further inquiry discovered that the patient was menstruating. We concluded that abnormal radioiodine uptake in menstrual uterus might be an exceptional finding mimicking a metastasis.

Publication types

  • Case Reports

MeSH terms

  • Adult
  • Biological Transport
  • False Positive Reactions
  • Female
  • Humans
  • Iodine Radioisotopes / metabolism*
  • Iodine Radioisotopes / therapeutic use
  • Menstruation / metabolism*
  • Single Photon Emission Computed Tomography Computed Tomography*
  • Thyroid Cancer, Papillary / metabolism
  • Thyroid Cancer, Papillary / physiopathology
  • Thyroid Cancer, Papillary / radiotherapy
  • Thyroid Cancer, Papillary / surgery
  • Thyroidectomy
  • Uterus / diagnostic imaging
  • Uterus / metabolism*
  • Uterus / physiopathology
  • Whole Body Imaging

Substances

  • Iodine Radioisotopes
  • Iodine-131