Both silicalite-1/SiC foam and ZSM-5/SiC foam may serve as novel bone replacement materials

Fengyu Hao; Cuicui Zhang; Lin Wu; Yong Gao; Yilai Jiao

doi:10.21037/atm.2019.05.06

Both silicalite-1/SiC foam and ZSM-5/SiC foam may serve as novel bone replacement materials

Ann Transl Med. 2019 Jun;7(12):255. doi: 10.21037/atm.2019.05.06.

Authors

Fengyu Hao¹, Cuicui Zhang², Lin Wu², Yong Gao³, Yilai Jiao³

Affiliations

¹ Department of Dental Materials, School of Stomatology, China Medical University, Shenyang 110001, China.
² Department of Prosthodontics, School of Stomatology, China Medical University, Shenyang 110001, China.
³ Institute of Metal Research, Chinese Academy of Sciences, Shenyang 110016, China.

Abstract

Background: This study aimed to analyze the bioactivity and biocompatibility of silicon carbide (SiC) foam coated with one of two kinds of zeolite.

Methods: The surface charges, protein adsorption ability and mineralization ability were compared between silicalite-1/SiC foam and ZSM-5/SiC foam.

Results: Proliferation and differentiation of primary osteoblasts seeded on two types of materials were significantly higher when compared with uncoated SiC foam after 7 d. There was no significant difference in the bioactivity between silicalite-1/SiC foam and ZSM-5/SiC foam. Silicalite-1/SiC foam and ZSM-5/SiC foam had no cytotoxic effect on primary osteoblasts.

Conclusions: These results suggest both silicalite-1/SiC foam and ZSM-5/SiC foam have the potential for use as novel bone replacement materials.

Keywords: Zeolite; bioactivity; bone replacement material; silicon carbide (SiC).