Recent Developments of Reverse Micellar Techniques for Lysozyme, Bovine Serum Albumin, and Bromelain Extraction

Mol Biotechnol. 2019 Oct;61(10):715-724. doi: 10.1007/s12033-019-00200-7.

Abstract

Biomolecules produced by living organisms can perform vast array of functions and play an important role in the cell. Important biomolecules such as lysozyme, bovine serum albumin (BSA), and bromelain are often studied by researchers due to their beneficial properties. The application of reverse micelles is an effective tool for protein separation from their sources due to the special system structure. Mechanisms of transferring biomolecules and factors that influence the extraction of biomolecules are reviewed in this paper. The enhancement of biomolecule extraction could be achieved depending on the properties of reverse micelles. This paper provides an overall review on lysozyme, BSA, and bromelain extraction by reverse micelle for various applications.

Keywords: Bovine serum albumin; Bromelain; Lysozyme; Protein separation; Reverse micelles.

Publication types

  • Review

MeSH terms

  • Animals
  • Bromelains / isolation & purification*
  • Cattle
  • Chemical Fractionation
  • Hydrogen-Ion Concentration
  • Micelles
  • Muramidase / isolation & purification*
  • Serum Albumin, Bovine / isolation & purification*
  • Surface-Active Agents / chemistry

Substances

  • Micelles
  • Surface-Active Agents
  • Serum Albumin, Bovine
  • Bromelains
  • Muramidase