Diagnostic Performance of Acoustic Radiation Force Impulse Elastography for the Differentiation of Benign and Malignant Superficial Lymph Nodes: A Meta-analysis

J Ultrasound Med. 2020 Feb;39(2):213-222. doi: 10.1002/jum.15096. Epub 2019 Jul 25.

Abstract

To estimate the diagnostic performance of acoustic radiation force impulse elastography in distinguishing between benign and malignant superficial lymph nodes, relevant articles published before October 31, 2018, in China and other countries were used. Conclusively, a total of 18 articles were analyzed. Sixteen studies used Virtual Touch tissue quantification (Siemens Healthineers, Erlangen, Germany), and 4 studies used Virtual Touch tissue imaging (Siemens Healthineers). After a meta-analysis, it was found that acoustic radiation force impulse elastography is an efficient method for detecting superficial lymph nodes. In addition, if the cutoff value for the shear wave velocity were less than 2.85 m/s, the summary sensitivity would increase, and the heterogeneity would be reduced.

Keywords: Virtual Touch tissue imaging quantification; acoustic radiation force impulse; elastography; lymph node; ultrasound.

Publication types

  • Meta-Analysis
  • Review

MeSH terms

  • Diagnosis, Differential
  • Elasticity Imaging Techniques / methods*
  • Humans
  • Lymphatic Metastasis / diagnostic imaging*
  • Lymphatic Metastasis / pathology*