Ectopic ACTH Syndrome in a Child With Abdominal Ewing Sarcoma: A Rare Paraneoplastic Phenomenon

J Pediatr Hematol Oncol. 2020 Oct;42(7):e668-e669. doi: 10.1097/MPH.0000000000001569.

Abstract

Ectopic adrenocorticotropic hormone syndrome is a paraneoplastic phenomenon rarely seen in pediatrics and rarely described in Ewing sarcoma. We report a 15-year-old boy with abdominal Ewing sarcoma and clinical and laboratory findings of ectopic adrenocorticotropic hormone syndrome that promptly resolved with treatment of the tumor.

Publication types

  • Case Reports

MeSH terms

  • ACTH Syndrome, Ectopic / etiology
  • ACTH Syndrome, Ectopic / pathology*
  • ACTH Syndrome, Ectopic / therapy
  • Abdominal Neoplasms / complications*
  • Abdominal Neoplasms / pathology
  • Adolescent
  • Adrenocorticotropic Hormone / metabolism
  • Bone Neoplasms / complications*
  • Bone Neoplasms / pathology
  • Humans
  • Male
  • Prognosis
  • Sarcoma, Ewing / complications*
  • Sarcoma, Ewing / pathology

Substances

  • Adrenocorticotropic Hormone