Modulating the cardiotoxic behaviour of immunoglobulin light chain dimers through point mutations

Amyloid. 2019;26(sup1):105-106. doi: 10.1080/13506129.2019.1583185.

Affiliations

¹ a Department of Bioscience, University of Milan , Milan , Italy.
² b Department of Nutritional Science, University of Milan , Milan , Italy.
³ c IRCCS-Istituto di Ricerche Farmacologiche "Mario Negri" , Milano , Italy.
⁴ d Amyloidosis Research and Treatment Center, Fondazione IRCCS Policlinico San Matteo , Pavia , Italy.
⁵ e Department of Chemistry, University of Cambridge , Cambridge , UK.

PMID: 31343361
DOI: 10.1080/13506129.2019.1583185

No abstract available

MeSH terms

Cardiotoxicity / complications
Cardiotoxicity / genetics*
Cardiotoxicity / pathology
Humans
Immunoglobulin Light Chains / chemistry
Immunoglobulin Light Chains / genetics*
Immunoglobulin Light-chain Amyloidosis / complications
Immunoglobulin Light-chain Amyloidosis / genetics*
Immunoglobulin Light-chain Amyloidosis / pathology
Point Mutation / genetics
Protein Multimerization / genetics
Proteostasis Deficiencies / complications
Proteostasis Deficiencies / genetics*
Proteostasis Deficiencies / pathology
Sequence Alignment

Substances

Immunoglobulin Light Chains