Three new flavonoids, pinocembrin-7-O-[3″-O-galloyl]-β-D-glucose (1), pinocembrin-7-O-[2″-O-galloyl-4″,6″-hexahydroxydiphenoyl]-β-D-glucose (2), 2',6'-dihydroxydihydrochalcone-4'-O-[2″-O-galloyl-4″,6″-hexahydroxydiphenoyl]-β-D-glucopyranoside (3), and 12 known compounds (4-15) were isolated from Penthorum Chinense Pursh. The structures of all compounds were established mainly by NMR and MS experiments as well as the necessary chemical evidence. The anti-hyperlipidemic activities of the three new flavonoids were predicted by molecular docking.
Keywords: Penthorum chinense; anti-hyperlipidemic activity; flavonoid; molecular docking.